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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human CD305 Antibody    

Anti-Human CD305 Antibody

Goat Anti-Human Polyclonal Antibody

  • WB - Anti-Human CD305 Antibody  ABD11266
    Human lymph node cell lysate probed with Goat anti Human CD305
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6GTX8
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 31412 Da
Additional Information
Purification Antiserum to human CD305 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide sequence C-NDTEDVSQASPSE from the internal region of CD305 (NP_002278.1; NP_068352.1).
Shelf Life 18 months from date of despatch.
Gene ID 3903
Other Names Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1, CD305
Target/Specificity Goat anti-Human CD305 antibody recognises human Leukocyte-associated immunoglobulin-like receptor 1, also known as CD305 or LAIR-1. CD305 is a 287 amino acid ~30kDa, single pass typeI transmembrane glycoprotein, expressed by natural killer cells, monocytes, dendritic cells, and T cells, and also by other hematopoeitic cells including B cells, but is not expressed by platelets or erythrocytes.Although structurally related to other killer cell inhibitory receptors, CD305 does not appear to recognize HLA class I, providing a novel mechanism of HLA class I-independent NK cell regulation. CD305 has been shown to inhibit proliferation, cellular activation and inflammation, and to induce apoptosis in myeloid leukemia cell lines, and found to be expressed at abnormally low levels in naive B cells from HIV-1 infected patients.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD305 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11266
(40 western blots)
Availability: Inquire
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