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Anti-Human Interleukin-15 Antibody

Rabbit Anti-Human Polyclonal Antibody

     
  • IHC - Anti-Human Interleukin-15 Antibody  ABD11275
    Staining of formalin fixed, paraffin embedded normal human placenta with Rabbit anti Human interleukin-15
  • IHC-P - Anti-Human Interleukin-15 Antibody  ABD11275
    Staining of formalin fixed, paraffin embedded normal human placenta with Rabbit anti Human interleukin-15
  • IHC-P - Anti-Human Interleukin-15 Antibody  ABD11275
    Staining of formalin fixed, paraffin embedded normal human placenta with Rabbit anti Human interleukin-15
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, IP, Func
Primary Accession P40933
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 18086 Da
Additional Information
Purification Antisera to human IL-15 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by antigen affinity chromatography.
Immunogen Recombinant human IL-15
Shelf Life 12 months from date of reconstitution.
Gene ID 3600
Other Names Interleukin-15, IL-15, IL15
Target/Specificity Rabbit anti-Human Interleukin-15 antibody recognizes human IL-15 (Interleukin-15), a 14kDa immunomodulatory glycoprotein expressed by multiple tissues and cell types, which primarily stimulates T lymphocytes, but is also critical for the development and activation of natural killer cells (NK).IL-15 shares functional properties with IL-2 and binds with high affinity to the IL-15 receptor (IL-15R), consisting of the IL-15R alpha chain, and also the IL-2Rbeta and common gamma chains used by the IL-2 receptor. Affects of IL-15 have been linked with cells and tissues unrelated to the immune system, and increased expression of IL-15 has been demonstrated in Rheumatoid Arthritis (RA), ulcerative colitis (UC) Chron’s disease (CD) and lymphoid malignancies, and also conditions affiliated with HIV and HTLV-1 infection.Rabbit anti-Human Interleukin-15 antibody will neutralise IL-15 activity in bioassay systems.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human Interleukin-15 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Kurys, G. et al. (2000) The long signal peptide isoform and its alternative processing direct the intracellular trafficking of interleukin-15.
J. Biol. Chem. 275: 30653 - 30659. 2. Fehniger, T.A. and Caligiuri, M.A. et al (2001) Interleukin 15: biology and relevance to human disease.
BLOOD. 97: 14-32.

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Cat# ABD11275
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