|Calculated MW||301367 Da|
|Purification||Antisera to human ATR peptide were raised by repeated immunisation of rabbits with highly purified antigen.|
|Immunogen||Human ATR peptide, amino acids 2122-2380|
|Shelf Life||18 months from date of despatch.|
|Other Names||Serine/threonine-protein kinase ATR, 188.8.131.52, Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1, ATR, FRP1|
|Target/Specificity||ABD11293 recognises the ATR (Ataxia telangiectasia and rad 3 related) protein, a 300kD protein kinase reported to have a role in recognising and responding to DNA strand interruptions during meiosis.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-ATR (aa2122-2380) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Keegan, K.S. et al. (1996) The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.Genes and Development 10: 2423-2437. 2. O'Driscoll, M. et al. (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome.Nat Genet. 33: 497-501.
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