|Application ||WB, E|
|Calculated MW||30717 Da|
|Purification||Antisera to ovine IL-1 beta were raised by repeated immunisation of rabbits with highly purified antigen.|
|Immunogen||Recombinant IL-1 beta.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-1 beta, IL-1 beta, IL1B|
|Target/Specificity||Rabbit anti-Sheep interleukin 1β antibody recognizes ovine interleukin-1 beta (IL-1 beta). No cross-reactivity is seen with ovine IL-6, IL-8, MCP-1 or TNF alpha.Rabbit anti-Sheep interleukin 1β antibody neutralizes the bioactivity of ovine IL-1 beta. Removal of sodium azide is recommended prior to use in functional assays.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Sheep Interleukin-1 beta Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Rothel, J.S. et al. (1997) Analysis of ovine IL-1 beta production in vivoandin vitro by enzyme immunoassay and immunohistochemistry.Vet. Immunol. Immunopathol. 57: 267-278. 2. Bannerman, D.D. et al.(2004)Escherichia coliandStaphylococcus aureus elicit differential innate immune responses following intramammary infection.Clin Diagn Lab Immunol. 11: 463-72. 3. Dernfalk, J. et al. (2007) The xMAP technique can be used for detection of the inflammatory cytokines IL-1beta, IL-6 and TNF-alpha in bovine samples.Vet Immunol Immunopathol. 118: 40-9. 4. Moyes, K.M. et al. (2009) Identification of potential markers in blood for the development of subclinical and clinical mastitis in dairy cattle at parturition and during early lactation.J Dairy Sci. 92: 5419-28. 5. Allen, J.S. et al. (2009) Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture.Diabetes. 2009 Jan;58(1):138-45. 6. Vordermeier, M. et al. (2012) Cytokine responses of Holstein and Sahiwal zebu derived monocytes after mycobacterial infection.Trop Anim Health Prod. 44: 651-5. 7. Xu, A. et al. (2015) The Ovine Fetal and Placental Inflammatory Response to Umbilical Cord Occlusions With Worsening Acidosis.Reprod Sci. pii: 1933719115580994. 8. Bagu, E.T. et al. (2010) Post-natal changes in testicular concentrations of interleukin-1 alpha and beta and interleukin-6 during sexual maturation in bulls.Reprod Domest Anim. 45 (2): 336-41. 9. Atik, A. et al. (2012) Long-term pulmonary effects of intrauterine exposure to endotoxin following preterm birth in sheep.Reprod Sci. 19 (12): 1352-64. 10. Silvestre, F.T. et al. (2011) Effects of differential supplementation of fatty acids during the peripartum and breeding periods of Holstein cows: II. Neutrophil fatty acids and function, and acute phase proteins.J Dairy Sci. 94 (5): 2285-301.
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