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Anti-Human IRAK1 (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • ICC - Anti-Human IRAK1 (C-Terminal) Antibody  ABD11314
    Immunocytochemical staining of HeLa cells with Rabbit anti Human IRAK-1
  • WB - Anti-Human IRAK1 (C-Terminal) Antibody  ABD11314
    Western Blot analysis of THP-1 and HeLa cell lysates probed with Rabbit anti Human IRAK-1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51617
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 76537 Da
Additional Information
Purification Antisera to human IRAK were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Immunogen Peptide from C terminus of human IRAK
Shelf Life 18 months from date of despatch.
Gene ID 3654
Other Names Interleukin-1 receptor-associated kinase 1, IRAK-1,, IRAK1, IRAK
Target/Specificity Rabbit anti-Human IRAK1 antibody recognizes human Interleukin-1 receptor-associated kinase 1 (IRAK1) an 80kD serine/threonine protein kinase designated IRAK containing a single protein kinase domain and a single death domain. IRAK is associated with IL-1 receptor subunits, and mediates a signalling cascade leading to NF-kB activation after IL-1 binding (Burnset al.2000).Multiple isoforms of IRAK1 generated by alternative splicing have been described. Isoforms 1 and 2 are ubiquitously expressed (Jensenet al.2001). Rabbit anti-Human IRAK1 antibody recognizes isoform 1 but reactivity with other isoforms having partial deletions of the carboxy-terminal region has not been assessed.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human IRAK1 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Cao, Z. et al. (1996) IRAK: a kinase associated with the interleukin-1 receptor.
Science 271: 1128-1131.

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Cat# ABD11314
(40 western blots)
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