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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-GFR alpha 2 Antibody    

Anti-GFR alpha 2 Antibody

  • WB - Anti-GFR alpha 2 Antibody  ABD11323
    Western blot analysis of HeLa total cell lysate probed with Rabbit anti Human GFR alpha 2
  • ICC - Anti-GFR alpha 2 Antibody  ABD11323
    Immunocytochemical staining of Hela cells with Rabbit anti Human GFR alpha 2
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00451
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 51544 Da
Additional Information
Other Species Rat,H,M
Purification Antisera to human GFR alpha-2 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Immunogen Synthetic peptide from C-terminus of human GFR alpha-2
Shelf Life 18 months from date of despatch.
Gene ID 2675
Other Names GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2, GFRA2, GDNFRB, RETL2, TRNR2
Target/Specificity ABD11323 recognises the cell surface receptor for neurturin, which was recently designated as GFR alpha-2. Neurturin is a member of the GDNF family, and has an important role in the control of vertebrate neuron survival and differentiation. GRF alpha-2 is a 52kD glycoprotein, and is a GPI-linked cell surface receptor.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-GFR alpha 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Kotzbauer, P.T. et al. (1996) Neurturin, a relative of glial cell-line derived neurotrophic factor.
Nature 384: 467-470.2. Klein, R.D. et al. (1997) A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor.
Nature 387: 717-721.3. Buj-Bello, A. et al. (1997) Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.
Nature 387: 721-724.4. GFRa Nomenclature Committee (1997) Nomenclature of GPI-linked receptors for the GDNF ligand family.
Neuron 19: 485.

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Cat# ABD11323
(40 western blots)
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