|Application ||WB, IHC-F|
|Calculated MW||51544 Da|
|Purification||Antisera to human GFR alpha-2 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.|
|Immunogen||Synthetic peptide from C-terminus of human GFR alpha-2|
|Shelf Life||18 months from date of despatch.|
|Other Names||GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2, GFRA2, GDNFRB, RETL2, TRNR2|
|Target/Specificity||ABD11323 recognises the cell surface receptor for neurturin, which was recently designated as GFR alpha-2. Neurturin is a member of the GDNF family, and has an important role in the control of vertebrate neuron survival and differentiation. GRF alpha-2 is a 52kD glycoprotein, and is a GPI-linked cell surface receptor.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-GFR alpha 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kotzbauer, P.T. et al. (1996) Neurturin, a relative of glial cell-line derived neurotrophic factor.Nature 384: 467-470.2. Klein, R.D. et al. (1997) A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor.Nature 387: 717-721.3. Buj-Bello, A. et al. (1997) Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.Nature 387: 721-724.4. GFRa Nomenclature Committee (1997) Nomenclature of GPI-linked receptors for the GDNF ligand family. Neuron 19: 485.
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