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Anti-MADD Antibody

Rabbit Anti-Human Polyclonal Antibody

  • ICC - Anti-MADD Antibody  ABD11324
    Immunocytochemical staining of human splenocytes with Rabbit anti Human MADD
  • WB - Anti-MADD Antibody  ABD11324
    Western blot analysis of whole cell lysates from the indicated cell lines probed with Rabbit anti Human MADD
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WXG6
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 183303 Da
Additional Information
Other Species M
Purification Antisera to human MADD were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Immunogen Synthetic peptide from C-terminus of human MADD
Shelf Life 18 months from date of despatch.
Gene ID 8567
Other Names MAP kinase-activating death domain protein, Differentially expressed in normal and neoplastic cells, Insulinoma glucagonoma clone 20, Rab3 GDP/GTP exchange factor, MADD {ECO:0000312|EMBL:AAB57735.1, ECO:0000312|HGNC:HGNC:6766}
Target/Specificity ABD11324 recognises the apoptosis related protein designated MADD (MAP kinase - activating death domain protein). MADD is associated with Type I TNF receptor via their death domains.In Western blots this antibody detects MADD as a 200-220kD protein.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-MADD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Yoshimura, S. et al. (2010) Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
J Cell Biol. 191: 367-81.1. Schievella, A. R. et al. (1997) MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase.
J. Biol. Chem. 272: 12069 - 12075.

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Cat# ABD11324
(40 western blots)
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