|Application ||WB, ICC|
|Calculated MW||55155 Da|
|Purification||Antisera to murine FLIP were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.|
|Immunogen||Synthetic peptide from C-terminus of murine FLIPL|
|Shelf Life||18 months from date of despatch.|
|Other Names||CASP8 and FADD-like apoptosis regulator, Caspase homolog, CASH, Caspase-eight-related protein, Casper, Caspase-like apoptosis regulatory protein, CLARP, Cellular FLICE-like inhibitory protein, c-FLIP, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, I-FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, CASP8 and FADD-like apoptosis regulator subunit p43, CASP8 and FADD-like apoptosis regulator subunit p12, Cflar, Cash|
|Target/Specificity||ABD11325 recognises the apoptosis related protein designated FLIP (FLICE inhibitory protein).FLIP interacts with the adaptor protein FADD, and with Caspase-8 (FLICE) and Caspase-10 (FLICE2) to inhibit apoptosis induced by death receptors including CD95, DR3, TRAIL-R and TNFR1.FLIP exists in 2 forms, FLIPs (short) and FLIPL (long). ABD11325 recognises only FLIPL.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse FLIP (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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