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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Mouse FLIP (C-Terminal) Antibody    

Anti-Mouse FLIP (C-Terminal) Antibody

Rabbit Anti-Mouse Polyclonal Antibody

  • WB - Anti-Mouse FLIP (C-Terminal) Antibody  ABD11325
    Western blot analysis of NIH/3T3 whole cell lysate probed with Rabbit anti Mouse FLIP
  • ICC - Anti-Mouse FLIP (C-Terminal) Antibody  ABD11325
    Immunocytochemical staining of NIH/3T3 cells with Rabbit anti Mouse FLIP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O35732
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 55155 Da
Additional Information
Purification Antisera to murine FLIP were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Immunogen Synthetic peptide from C-terminus of murine FLIPL
Shelf Life 18 months from date of despatch.
Gene ID 12633
Other Names CASP8 and FADD-like apoptosis regulator, Caspase homolog, CASH, Caspase-eight-related protein, Casper, Caspase-like apoptosis regulatory protein, CLARP, Cellular FLICE-like inhibitory protein, c-FLIP, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, I-FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, CASP8 and FADD-like apoptosis regulator subunit p43, CASP8 and FADD-like apoptosis regulator subunit p12, Cflar, Cash
Target/Specificity ABD11325 recognises the apoptosis related protein designated FLIP (FLICE inhibitory protein).FLIP interacts with the adaptor protein FADD, and with Caspase-8 (FLICE) and Caspase-10 (FLICE2) to inhibit apoptosis induced by death receptors including CD95, DR3, TRAIL-R and TNFR1.FLIP exists in 2 forms, FLIPs (short) and FLIPL (long). ABD11325 recognises only FLIPL.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse FLIP (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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2. Zhang, J. et al. (2001) Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis.
J Immunol. 166: 4981-6.1. Irmler, M. et al. (1997) Inhibition of death receptor signals by cellular FLIP.
Nature 388: 190-195.

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Cat# ABD11325
(40 western blots)
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