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Anti-Mouse ICAD (N-Terminal) Antibody

Rabbit Anti-Mouse Polyclonal Antibody

  • IHC - Anti-Mouse ICAD (N-Terminal) Antibody  ABD11327
    Immunohistochemical staining of mouse lung with Rabbit anti Mouse ICAD
  • WB - Anti-Mouse ICAD (N-Terminal) Antibody  ABD11327
    Western blot analysis of mouse lung lysate probed with Rabbit anti Mouse ICAD
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O54786
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 36572 Da
Additional Information
Purification Antisera to murine ICAD were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to amino acids 2-21 of mouse ICAD
Shelf Life 18 months from date of despatch.
Gene ID 13347
Other Names DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD, Dffa, Icad
Target/Specificity ICAD (Inhibitor of Caspase-Activated Dnase) is the murine homologue of human DFF-45.ICAD is cleaved by Caspase-3, releasing CAD which eventually causes degradation of DNA in the nucleus.ABD11327 recognises a 45kD band in Western blots.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse ICAD (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Enari, M. et al. (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.
Nature 391: 43-50.2. Sakahira, H. et al. (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis.
Nature 391: 96-99.3. Wyllie, A. (1998) Apoptosis: An endonuclease at last.
Nature 391: 20-21.

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Cat# ABD11327
(40 western blots)
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