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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human CD262 Antibody    

Anti-Human CD262 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human CD262 Antibody  ABD11330
    Western blot analysis of whole cell lysates from HeLa (H) and K562 (K) cells probed with Rabbit anti Human CD262
  • ICC - Anti-Human CD262 Antibody  ABD11330
    Immunocytochemical staining of HeLa cells with Rabbit anti Human CD262
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14763
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 47878 Da
Additional Information
Purification Antisera to human CD262 (DR5) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to amino acids 388-407 of human CD262 (DR5)
Shelf Life 18 months from date of despatch.
Gene ID 8795
Other Names Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2, CD262, TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Target/Specificity Rabbit anti-Human CD262 antibody recognizes human Tumor necrosis factor receptor superfamily member 10B, also known as CD262, Death receptor 5 or TNF-related apoptosis-inducing ligand receptor 2. CD262 is a 385 amino acid ~60 kDa single pass type ! transmembrane protein acting as a Receptor for the cytotoxic ligand TNFSF10/TRAIL.Mutations in the TNFRSF10B gene has been implicated in the development of Squamous cell carcinoma of the head and neck (HNSCC) a non melanoma cancer affecting the head and neck.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD262 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Chaudhary, P.M. et al. (1997) Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway.
Immunity. 7 (6): 821-30.

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Cat# ABD11330
(40 western blots)
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