|Application ||WB, IHC-F|
|Calculated MW||48275 Da|
|Purification||Antisera to calreticulin were raised by repeated immunisation of goats with highly purified antigen.|
|Immunogen||Purified rabbit skeletal muscle calreticulin.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, CALR|
|Target/Specificity||Goat anti-calreticulin antibodyrecognises calreticulin, a 418 aminoacid ~60 kDa Ca2+ binding chaperone involved in protein modification and folding within the endoplasmic reticulum (UniProt: P15253).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Calreticulin Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Milner, R.E. et al. (1991) Calreticulin and not Calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum.J. Biol. Chem. 266: 7155-7165. 2. Michalak, M. et al. (1991) Identification and immunolocalization of Calreticulin in pancreatic cells: no evidence for 'Calciosomes'.Exp. Cell. Res. 197: 91-99. 3. Santer, D.M. et al. (2010) C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes.J Immunol. 185: 4738-49.
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