|Application ||IHC-P, IHC-F|
|Purification||Antisera to serotonin were raised by repeated immunisation of rabbits with highly purified antigen.|
|Immunogen||Serotonin conjugated to bovine thyroglobulin|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Serotonin (also known as 5-hydroxytryptamine or 5-HT) is a biochemical messenger and neurotransmitter synthesized from L-tryptophan. Serotonin has a range of functions, including regulation of gastric motility, and may be related to some psychiatric disorders including schizophrenia and depression.Serotonin is widely distributed in the central and peripheral nervous system, and also in some non-neural tissues such as platelets.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3); 1% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Serotonin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Pönicke, K. et al. (2012) On the presence of serotonin in mammalian cardiomyocytes.Mol Cell Biochem. 365: 301-12. 2. Endepols, H. et al. (2006) The septal complex of the fire-bellied toad Bombina orientalis: chemoarchitecture.J Chem Neuroanat. 31: 59-76. 3. Dizdar, V. et al. (2010) Relative importance of abnormalities of CCK and 5-HT (serotonin) in Giardia-induced post-infectious irritable bowel syndrome and functional dyspepsia.Aliment Pharmacol Ther. 31: 883-91. 4. Dicke, U. et al. (1997) 5-HT-like immunoreactivity in the brains of plethodontid and salamandrid salamanders (Hydromantes italicus, Hydromantes genei, Plethodon jordani, Desmognathus ochrophaeus, Pleurodeles waltl): an immunohistochemical and biocytin double-labelling study.Cell Tissue Res. 287: 513-23. 5. Wheatcroft, J. et al. (2005) Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction.Neurogastroenterol Motil. 17: 863-70.
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