|Calculated MW||39280 Da|
|Purification||Antisera to CDw186 (CT) were raised by repeated immunisation of rabbit with highly purified antigen. Ig fraction prepared by ammonium sulphate precipitation|
|Immunogen||Peptide corresponding to amino acids 319 to 338 of human CDw186/CXCR6/Bonzo (CT).|
|Shelf Life||18 months from date of despatch.|
|Other Names||C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, CD186, CXCR6, BONZO, STRL33, TYMSTR|
|Target/Specificity||Rabbit anti-Human CD186 antibody recognizes the C-terminal region of the orphan G-coupled chemokine receptor CXCR6, also known as CDw186. CXCR6 has been identified as a co-receptor for simian immunodeficiency virus (SIV), HIV-2 and HIV-1. Lymphoid tissues and activated peripheral blood lymphocytes express CXCR6 mRNA.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD186 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Liao, F. et al. (1997) STRL33, A novel chemokine receptor-like protein functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1.J. Exp. Med. 185: 2015-23
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