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Anti-Human AIF (aa109-122) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • ICC - Anti-Human AIF (aa109-122) Antibody  ABD11360
    Immunocytochemical staining of Jurkat Tcell lymphoblast like cells with Rabbit anti Human AIF
  • WB - Anti-Human AIF (aa109-122) Antibody  ABD11360
    Western blot analysis of AIF in K562 cell lysate probed with Rabbit anti Human AIF antibody
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95831
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 66901 Da
Additional Information
Purification Antisera to AIF (NT) were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.
Immunogen Peptide corresponding to amino acids 109 - 122 of human AIF (NT).
Shelf Life 18 months from date of despatch.
Gene ID 9131
Other Names Apoptosis-inducing factor 1, mitochondrial, 1.1.1.-, Programmed cell death protein 8, AIFM1, AIF, PDCD8
Target/Specificity Rabbit anti-Human AIF antibody recognizes human apoptosis-inducing factor 1, mitochondrial, also known as AIF or programmed cell death protein 8. Human AIF is a 613 amino acid mitochondrial protein bearing a 54 amino acid N-terminal transit peptide and a 47 amino acid propeptide region adjacent. The mature peptide is a 512 amino acid ~67 kDa mitochondrial intermembrane space protein formed during apoptosis. Rabbit anti-Human AIF antibody reacts with the N-terminal region of the mature protein. AIF is widely expressed in human tissues and is released to the cytoplasm and then translocates to the nucleus on certain death signals where it is involved in the induction of nuclear apoptosis (Kimet al.2006).
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human AIF (aa109-122) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Susin. S.A. et al. (1999) Molecular characterization of mitochondrial apoptosis - inducing factor.
Nature. 397: 441-6.

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Cat# ABD11360
(40 western blots)
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