|Calculated MW||71845 Da|
|Purification||Antisera to DR6 (NT) were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Peptide corresponding to amino acids 42-56 of human DR6 precursor.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor receptor superfamily member 21, Death receptor 6, CD358, TNFRSF21, DR6|
|Target/Specificity||Rabbit anti-Human DR6 antibody recognizes human Tumor necrosis factor receptor superfamily member 21, also known as death domain containing receptor DR6, Death receptor 6 or CD358. DR6 is a 655 amino acid ~72 kDa type 1 single pass transmembrane glycoprotein with four extracellular cysteine rich repeats and a single cytoplasmic death domain. DR6 is widely expressed in human tissues and cell lines. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK (Panet al.1998).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃. DO NOT FREEZE.|
|Precautions||Anti-Human DR6 (aa42-56) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Achiron, A. et al. (2009) Molecular profiling of glatiramer acetate early treatment effects in multiple sclerosis.Dis Markers. 27: 63-73.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.