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>   home   >   Products   >   Primary Antibodies   >   Anti-8-Hydroxyguanosine Antibody (Serum)   

Anti-8-Hydroxyguanosine Antibody (Serum)

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Additional Information
Purification Antisera to 8-Hydroxyguanosine were raised by repeated immunisation of goat with highly purified antigen.
Immunogen 8-Hydroxyguanosine - conjugate
Shelf Life 18 months from date of despatch.
Target/Specificity ABD11367 recognises 8-hydroxyguanosine (8-OG), a modified base which occurs in DNA as a result of oxidative stress. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels of 8-OHdG have been shown to increase on exposure to ionizing radiation and tobacco smoke. ABD11367 cross reacts completely with 8-OHdG.ABD11367 does not cross react with other naturally occurring nucleotides.
Preservative & Stabilisers 0.1% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-8-Hydroxyguanosine Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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References

1. Dwivedi, S. et al. (2012) Butachlor induced dissipation of mitochondrial membrane potential, oxidative DNA damage and necrosis in human peripheral blood mononuclear cells
Toxicology. 302: 77-87. 2. Dwivedi, S. et al. (2012) Characterization of coal fly ash nanoparticles and induced oxidative DNA damage in human peripheral blood mononuclear cells.
Sci Total Environ. 437: 331-8.

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Cat# ABD11367
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