|Application ||WB, IHC-P, IF, E|
|Calculated MW||100409 Da|
|Purification||Antisera to Synphilin-1 were raised by repeated immunisation of goat with highly purified antigen.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Synphilin-1, Sph1, Alpha-synuclein-interacting protein, SNCAIP|
|Target/Specificity||ABD11368 recognises synphilin-1, a cytoplasmic protein which associates with alpha-synuclein in vivo. Alpha-Synuclein is a major component of lewy bodies in patients with sporadic Parkinson's disease (PD) and mutations of alpha-synuclein are involved in familial forms of PD. Reports suggest that synphilin-1 may play a role in lewy body formation in association with alpha synuclein.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Synphilin 1 Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Buttner, S. et al. (2010) Synphilin-1 enhances a-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner.PloS ONE 5: e13700.
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