|Calculated MW||31350 Da|
|Purification||Antisera to CAPZB were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide NDLVEALKRKQQC corresponding to the C-terminus of CAPZB (NP_004921).|
|Shelf Life||18 months from date of despatch.|
|Other Names||F-actin-capping protein subunit beta, CapZ beta, CAPZB|
|Target/Specificity||Goat anti-Human CAPZB antibody recognizes human F-actin capping protein muscle Z-line beta also known as CapZ beta or CAPZB. CAPZB is a member of the F-actin capping protein family involved in the growth regulation of actin filaments by binding to the barbed ends of fast growing actin filaments (Baiet al.2011).|
|Preservative & Stabilisers||0.02% Sodium Azide; 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CAPZB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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2. Masszi, A. et al. (2010) Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3.J Cell Biol. 188: 383-99.1. Barron-Casella, E. A. et al. (1995) Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families.J. Biol. Chem. 270: 21472 - 21479.
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