|Application ||WB, IHC-P|
|Calculated MW||78928 Da|
|Purification||Antisera to human Tau were raised by repeated immunisations of goats with highly purified antigen.|
|Immunogen||Synthetic peptide MAEPRQEFEVMEDHAG corresponding to amino acids 1-16 of human Tau.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU|
|Target/Specificity||Goat anti-Human tau antibody recognizes the N-terminal region of human Microtubule-associated protein tau, also known as tau, Neurofibrillary tangle protein or Paired helical filament-tau. Tau is a a ~50-70 kDa heterogeneous group of proteins that are involved in microtubule assembly. In healthy brain tissue tau is localized to the axons of neurons.Tau has been associated with some neurological disease states including Alzheimer's disease where it localizes to neurofibrillary tangles (Goedertet al.1989).Several isoforms of human tau can be generated by alternative splicing, Goat anti-Human tau antibody is expected to recognize all isoforms with the possible exception of isoform-3 which demonstrates multiple residue changes within the region of the immunizing peptide.|
|Preservative & Stabilisers||0.1% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human tau (aa1-16) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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