|Calculated MW||55711 Da|
|Purification||Antisera to human BACE1 (C-terminal) were raised by repeated immunisations of goats with highly purified antigen.|
|Immunogen||Synthetic peptide CLRQQHDDFADDISLLK corresponding to the C-terminal amino sequence 458-501 of human BACE.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Beta-secretase 1, 220.127.116.11, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149|
|Target/Specificity||Goat anti-BACE1 antibody recognizes human beta-site APP-cleaving enzyme 1, also known as beta- secretase 1, BACE1, Aspartyl protease 2, Asp2 or Memapsin-2. BACE1 is a 501 amino acid, the aminio terminal 45 residues constituting the signal and propeptide moieties, ~70 kDa aspartic protease.BACE1 is involved in the cleavage of the amyloid precursor protein (APP) leading to the generation and extracellular release of soluble amyloid beta peptide (Linet al.2000). Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease (Vassaret al.1999).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human BACE1 (C-Terminal) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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