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Anti-Human BACE1 (C-Terminal) Antibody (Serum)

Goat Anti-Human Polyclonal Antibody

  • IHC - Anti-Human BACE1 (C-Terminal) Antibody (Serum) ABD11419
    Goat anti Human Bace1 antibody used for the detection of BACE1 in neurons on formalin fixed, paraffin embedded hippocampus sections from a patient with Alzheimer's disease
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P56817
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 55711 Da
Additional Information
Purification Antisera to human BACE1 (C-terminal) were raised by repeated immunisations of goats with highly purified antigen.
Immunogen Synthetic peptide CLRQQHDDFADDISLLK corresponding to the C-terminal amino sequence 458-501 of human BACE.
Shelf Life 18 months from date of despatch.
Gene ID 23621
Other Names Beta-secretase 1,, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
Target/Specificity Goat anti-BACE1 antibody recognizes human beta-site APP-cleaving enzyme 1, also known as beta- secretase 1, BACE1, Aspartyl protease 2, Asp2 or Memapsin-2. BACE1 is a 501 amino acid, the aminio terminal 45 residues constituting the signal and propeptide moieties, ~70 kDa aspartic protease.BACE1 is involved in the cleavage of the amyloid precursor protein (APP) leading to the generation and extracellular release of soluble amyloid beta peptide (Linet al.2000). Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease (Vassaret al.1999).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human BACE1 (C-Terminal) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11419
(40 western blots)
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