|Calculated MW||55711 Da|
|Purification||Antisera to human BACE1 (C-terminal) were raised by repeated immunisations of goats with highly purified antigen.|
|Immunogen||Synthetic peptide CLRQQHDDFADDISLLK corresponding to the C-terminal amino sequence 458-501 of human BACE.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Beta-secretase 1, 188.8.131.52, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149|
|Target/Specificity||Goat anti-BACE1 antibody recognizes human beta-site APP-cleaving enzyme 1, also known as beta- secretase 1, BACE1, Aspartyl protease 2, Asp2 or Memapsin-2. BACE1 is a 501 amino acid, the aminio terminal 45 residues constituting the signal and propeptide moieties, ~70 kDa aspartic protease.BACE1 is involved in the cleavage of the amyloid precursor protein (APP) leading to the generation and extracellular release of soluble amyloid beta peptide (Linet al.2000). Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease (Vassaret al.1999).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human BACE1 (C-Terminal) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.