|Application ||WB, IHC-P, E, Func|
|Calculated MW||11342 Da|
|Purification||Antisera to human GRO-gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Recombinant human GRO-gamma (PHP117)|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||C-X-C motif chemokine 3, GRO-gamma(1-73), Growth-regulated protein gamma, GRO-gamma, Macrophage inflammatory protein 2-beta, MIP2-beta, GRO-gamma(5-73), CXCL3, GRO3, GROG, SCYB3|
|Target/Specificity||Rabbit anti-Human GRO gamma antibody recognizes human GRO-gamma, also known as CXCL3, Growth-regulated protein gamma, GRO-gamma(1-73), Macrophage inflammatory protein 2-beta or MIP2-beta. GRO gamma is a ~7.9kDa CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils.Like GRO-alpha (CXCL1) and GRO-beta (CXCL2), GRO-gamma contains the ELR-motif (N-Terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, though studies have shown a difference in the potency and receptor binding affinity of these three proteins (Wuytset al.1999).|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human GRO gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kogan-Sakin, I. et al. (2009) Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1.Carcinogenesis 30: 698-705.1. Haskill, S. et al. (1990) Identification of three related human GRO genes encoding cytokine functions.Proc Natl Acad Sci U S A. 87 (19): 7732-6.2. Geiser, T. et al. (1993) The Interleukin-8-related chemotactic cytokines GROalpha, GRObeta, and GROgamma activate human neutrophil and basophil leukocytes. J. Biol. Chem. 268: 15419-15424.
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