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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human MCP-2 Antibody    

Anti-Human MCP-2 Antibody

Rabbit Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E, Func
Primary Accession P80075
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 11246 Da
Additional Information
Purification Antisera to human MCP-2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human MCP-2.
Shelf Life 12 months from date of reconstitution.
Gene ID 6355
Other Names C-C motif chemokine 8, HC14, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, MCP-2(6-76), CCL8, MCP2, SCYA10, SCYA8
Target/Specificity Rabbit anti-Human MCP-2 antibody recognizes human MCP-2 (Monocyte Chemoattractant Protein 2), otherwise known as CCL8, a 76 amino acid CC chemokine originally isolated from the human osteosarcoma cell line MG-63, which is expressed at highest levels in peripheral blood cells and the small intestine.MCP-2 acts as a chemoattractant for monocytes, lymphocytes, eosinophils and basophils, due to its ability to bind to the common MCP receptor, chemokine (C-C motif) receptor 2 (CCR2), and also CCR1 and CCR3. Proteolytic cleavage of MCP-2 into the NH2-Terminally truncated form, MCP-2 (6-76), results in the loss of chemotactic activity, forming a functional C-C chemokine inhibitor, which may be important during inflammatory responses.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human MCP-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Van Damme, J. et al. (1992) Structural and functional identification of two human, tumor-derived monocytes chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family.
J. Exp. Med. 176: 59-65.

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Cat# ABD11425
(40 western blots)
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