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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human MIP-1 alpha Antibody    

Anti-Human MIP-1 alpha Antibody

Goat Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10147
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 10085 Da
Additional Information
Purification Antisera to human MIP-1 alpha were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human MIP-1 alpha.
Shelf Life 12 months from date of reconstitution.
Gene ID 6348
Other Names C-C motif chemokine 3, G0/G1 switch regulatory protein 19-1, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, PAT 464.1, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha(4-69), LD78-alpha(4-69), CCL3, G0S19-1, MIP1A, SCYA3
Target/Specificity Goat anti-Human MIP-1 alpha antibody recognizes human MIP-1 alpha, otherwise known as CCL3, a 69 amino acid member of the CC chemokine family which plays a critical role in haematopoiesis and is shown to signal through the chemokine receptors CCR1, CCR4 and CCR5.MIP-1 alpha is also involved in host defence against invading pathogens, acting as a regulator of activation and trafficking of inflammatory cells, such as macrophages, NK cells, granulocytes, dendritic cells and CD8+ lymphocytes. The recruitment of inflammatory cells by MIP-1 alpha, has been linked with the pathogenesis of several diseases, including rheumatoid arthritis, H. pylori associated gastritis and bacterial meningitis.The secretion of MIP-1 alpha by CD8+ lymphocytes acts as a major HIV-suppressive factor (HIV-SF) through binding to CCR5, identified as a coreceptor for HIV-1 target cell entry.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human MIP-1 alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Cocchi, F. et al. (1996) Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells.
Science 274: 1393-1395.1. Menten, P. et al. (2002) Macrophage inflammatory protein-1.
Cyt. Growth Factor 13: 455-481.

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Cat# ABD11426
(40 western blots)
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