|Application ||IHC-P, E|
|Calculated MW||47330 Da|
|Purification||Antisera to human casein kinase 1 delta were raised by repeated immunisations of goats with highly purified antigen.|
|Immunogen||Synthetic peptide corresponding to amino acids 310-327 of human casein kinase 1 delta|
|Shelf Life||18 months from date of despatch.|
|Other Names||Casein kinase I isoform delta, CKI-delta, CKId, 126.96.36.199, Tau-protein kinase CSNK1D, 188.8.131.52, CSNK1D, HCKID|
|Target/Specificity||Goat anti-Human casein kinase 1 delta antibody recognizes human casein kinase 1 delta, also known as protein kinase CK1 delta or Tau-protein kinase CSNK1D.Casein kinase 1 delta is a 415 amino acid ~47 kDa member of the casein kinase 1 family of protein kinases common to all eukaryotic cells, although tissue distribution and subcellular localisation may vary between isoforms. Casein kinase 1 delta has been implicated in the regulation of p53 (Venerandoet al.2010). Upregulation of casein kinase 1 delta expression has been reported in Alzheimer's disease hippocampus and its association with tau-containing bodies suggests that it may play a role in the abnormal phosphorylation of tau (Liet al.2005).|
|Preservative & Stabilisers||0.1% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Casein Kinase 1 delta (C-Terminal) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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1. Babiker, A.A. et al. (2006) Overexpression of ecto-protein kinases in prostasomes of metastatic cell origin.Prostate. 66: 675-86.
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