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Anti-Human RAD50 (aa480-724) Antibody (Serum)

Sheep Anti-Human Polyclonal Antibody

     
  • WB - Anti-Human RAD50 (aa480-724) Antibody (Serum) ABD11432
    HeLa Nuclear Extract probed with Sheep anti RAD50
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession Q92878
Reactivity Human
Host Sheep
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 153892 Da
Additional Information
Purification Antisera to human Rad50 were raised by repeated immunisations of sheep with highly purified antigen.
Immunogen Recombinant Rad50 fragment (aa480 - 724).
Shelf Life 18 months from date of despatch.
Gene ID 10111
Other Names DNA repair protein RAD50, hRAD50, 3.6.-.-, RAD50
Target/Specificity Sheep anti-Human RAD50 antibody recognizes human Rad50, a component of Mre11/Rad50/Nbs1 complex involved in DNA double strand break repair. Rad50 in co-operation with Nbs1 and Mre11 may also be involved in cell cycle checkpoint activation, telomere maintenance and meiotic recombination.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human RAD50 (aa480-724) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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References

1. Goldberg, M. et al. (2003) MDC1 is required for the intra-S-phase DNA damage checkpoint.
Nature. 421: 952 - 956 2. Dolganov, G.M. et al. (1996) Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.
Mol. Cell. Biol. 16: 4832 - 41.

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Cat# ABD11432
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