|Application ||WB, IP|
|Calculated MW||153892 Da|
|Purification||Antisera to human Rad50 were raised by repeated immunisations of sheep with highly purified antigen.|
|Immunogen||Recombinant Rad50 fragment (aa480 - 724).|
|Shelf Life||18 months from date of despatch.|
|Other Names||DNA repair protein RAD50, hRAD50, 3.6.-.-, RAD50|
|Target/Specificity||Sheep anti-Human RAD50 antibody recognizes human Rad50, a component of Mre11/Rad50/Nbs1 complex involved in DNA double strand break repair. Rad50 in co-operation with Nbs1 and Mre11 may also be involved in cell cycle checkpoint activation, telomere maintenance and meiotic recombination.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human RAD50 (aa480-724) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Goldberg, M. et al. (2003) MDC1 is required for the intra-S-phase DNA damage checkpoint.Nature. 421: 952 - 956 2. Dolganov, G.M. et al. (1996) Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.Mol. Cell. Biol. 16: 4832 - 41.
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