|Application ||WB, IP|
|Calculated MW||153892 Da|
|Purification||Antisera to human Rad50 were raised by repeated immunisations of sheep with highly purified antigen.|
|Immunogen||Recombinant Rad50 fragment (aa480 - 724).|
|Shelf Life||18 months from date of despatch.|
|Other Names||DNA repair protein RAD50, hRAD50, 3.6.-.-, RAD50|
|Target/Specificity||Sheep anti-Human RAD50 antibody recognizes human Rad50, a component of Mre11/Rad50/Nbs1 complex involved in DNA double strand break repair. Rad50 in co-operation with Nbs1 and Mre11 may also be involved in cell cycle checkpoint activation, telomere maintenance and meiotic recombination.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human RAD50 (aa480-724) Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Goldberg, M. et al. (2003) MDC1 is required for the intra-S-phase DNA damage checkpoint.Nature. 421: 952 - 956 2. Dolganov, G.M. et al. (1996) Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.Mol. Cell. Biol. 16: 4832 - 41.
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