|Calculated MW||57241 Da|
|Purification||Antisera to FLVCR2 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography on Protein A.|
|Immunogen||Synthetic peptide derived from external loop 3.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Feline leukemia virus subgroup C receptor-related protein 2, Calcium-chelate transporter, CCT, FLVCR2, C14orf58|
|Target/Specificity||Rabbit anti-Human FLVCR2 antibody recognises Feline leukemia virus subgroup C receptor-related protein 2, also known as FLVCR2, Pituitary Growth/Lactation Coupled (PG/LC) Transporter or Calcium-chelate transporter. FLVCR2 is expressed in cells of the pituitary gland that secrete growth hormone and/or prolactin, and also in other cells and tissues involved in calcium homeostasis. The structure of FLVCR2 contains novel hexad repeats that may be important for protein - protein interaction.There is increasing evidence that FLVCR2 is expressed by pericytes in the brain and may be vital for endothelial function of capillaries (Brasier et al.2004).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human FLVCR2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Brasier, G. et al. (2004) Novel hexad repeats conserved in a putative transporter with restricted expression in cell types associated with growth, calcium exchange and homeostasis.Exp. Cell Res. 293: 31-42.1. Duffy, S.P. et al. (2010) The Fowler syndrome-associated protein FLVCR2 is an importer of heme.Mol Cell Biol. 30: 5318-24.2. Thomas, S. et al. (2010) High-throughput sequencing of a 4.1?Mb linkage interval reveals FLVCR2 deletions and mutations in lethal cerebral vasculopathy.Hum Mutat. 31: 1134-41.
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