|Application ||WB, IF|
|Calculated MW||92469 Da|
|Other Species||B,Sh,Cynomolgus Pr,Pig|
|Purification||Antisera to human GRP94 were raised by repeated immunisation of rabbits with highly purified antigen.|
|Immunogen||Synthetic peptide derived from the internal sequence of human GRP94 conjugated to KLH|
|Shelf Life||18 months from date of despatch.|
|Other Names||Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog, HSP90B1, GRP94, TRA1|
|Target/Specificity||Rabbit anti-Human GRP94 antibody recognizes the 94 kDa glucose regulated protein, GRP94, also known as tumour rejection antigen (gp96). GRP94 is an endoplasmic reticulum resident molecular chaperone, a paralog of cytoplasmic Hsp90. GRP94 assists in the folding of membrane-bound proteins including the Toll-like receptors, certain subclasses of integrins and some secreted proteins such as IgG.Rabbit anti-Human GRP94 antibody detects a band of ~105 kDa in cynomolgus monkey brain lysates by western blotting.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human GRP94 Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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1. Yang, M. et al. (2015) A hyposensitive anticancer drug induces higher surface expression and release of heat shock proteins in a human hepatocellular carcinoma cell line.Mol Med Rep. 12 (2): 2879-85.
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