|Calculated MW||12580 Da|
|Purification||Antisera to human 4EBP1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a region within human 4EBP1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1|
|Target/Specificity||ABD11450 is specific for human eukaryotic translation initiation factor 4E binding protein 1 (4EBP1). 4EBP1 is principally expressed in the cytoplasm, and has a role in translation regulation. 4EBP1 binds to eukaryotic translation initiation factor 4E (eIF4E), which prevents the formation of the active eIF4E complex. Hyperphosphorylation of 4EBP1 results in the release of eIF4E, thus allowing the translation complex to assemble.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-4EBP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Schaeffer, V. et al. (2011) Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline.J Surg Res. 2011171: 769-76.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.