|Application ||IHC-F, IP|
|Calculated MW||45809 Da|
|Purification||Antisera to human Aurora A Kinase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a region of human Aurora A Kinase encoded within exon 5.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Aurora kinase A, 18.104.22.168, Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A, AURKA|
|Target/Specificity||Rabbit anti-Human aurora-A kinase antibody human aurora A kinase, also known as Serine/Threonine Kinase 6, STK6, Breast tumor-amplified kinase, ARK-1, Serine/threonine-protein kinase 15 or Aurora/IPL1-related kinase 1. Aurora A kinase is a cell-cycle regulated kinase that has an important role in centrosome maturation and chromosome segregation. This protein is found at the centrosome in interphase cells and at the spindle poles in mitosis.Aurora A inase is frequently overexpressed in various human carcinomas, which would suggest that this protein may be involved in tumorigenesis (Bischoff et al.1998).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Aurora-A Kinase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Dutta-Simmons, J. et al. (2009) Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression.Blood. 114: 2699-708.
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