|Application ||WB, IP|
|Calculated MW||54434 Da|
|Purification||Antisera to human CHK1 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a region within human CHK1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Serine/threonine-protein kinase Chk1, 18.104.22.168, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1, CHEK1, CHK1|
|Target/Specificity||Goat anti-Human Chk1 antibody recognizes human Serine/threonine-protein kinase Chk1, also known as cell cycle checkpoint kinase homologue 1, CHK1 or Checkpoint kinase-1. CHK1 is a 476 amino acid ~56 kDa cytoplasmic and nuclear protein.CHK1 has an important role at the G2 checkpoint in the cell cycle. CHK1 is activated in response to DNA damage, and serves to phosphorylate Cdc25, which results in cell cycle arrest.CHK1 may also play a role in the S phase checkpoint (Heffernanet al.2002).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Chk1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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