|Calculated MW||45144 Da|
|Purification||Antisera to human CKII alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a region of human CKII alpha encoded within exon 3.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Casein kinase II subunit alpha, CK II alpha, 188.8.131.52, CSNK2A1, CK2A1|
|Target/Specificity||Rabbit anti-Human Casein Kinase 2 alpha antibody recognizes human casein kinase II alpha, also known as CKIIa or Casein kinase II subunit alpha. CKIIa is a 391 amino acid ~42 kDa protein which localises to the endoplasmic reticulum and Golgi apparatus. CKII is ubiquitous composed of three subunits (alpha, alpha prime and beta) which form a tetrameric holoenzyme with 2 alpha, alpha' subunits or one of each together with two beta subunits (Lozemanet al1990). The alpha and alpha prime subunits are catalytic whilst the beta subunit appears to have a regulatory role (Ermakovaet al.2003).CKII is involved in the regulation of numerous pathways, including signal transduction, cell cycle and some metabolic pathways|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Casein Kinase 2 alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.