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Anti-Human RFC3 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human RFC3 Antibody  ABD11460
    Detection of human RFC3 in nuclear extracts of HeLa cells by western blotting with Rabbit anti Human RFC3
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40938
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 40556 Da
Additional Information
Purification Antisera to human RFC3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to a region within human RFC3.
Shelf Life 18 months from date of despatch.
Gene ID 5983
Other Names Replication factor C subunit 3, Activator 1 38 kDa subunit, A1 38 kDa subunit, Activator 1 subunit 3, Replication factor C 38 kDa subunit, RF-C 38 kDa subunit, RFC38, RFC3
Target/Specificity Rabbit anti-Human RFC3 antibody recognizes human Replication factor C subunit 3, also known as RFC3, Activator 1 38 kDa subunit, Replication factor C 38 kDa subunit or RFC38. RFC3 is a 356 amino acid ~38 kDa DNA binding protein found in several protein complexes critical for DNA replication and repair. Replication factor C (RFC) is a heteropentameric complex consisting of one large subunit, RFC1, and four small subunits, RFC2, RFC3, RFC4 and RFC5. This complex is required for efficient loading of PCNA onto DNA templates during processive DNA synthesis.A second RFC-related related complex is formed from interactions between Rad24, RFC2, RFC3, RFC4 and RFC5. This complex serves to load the heterotrimeric DNA damage checkpoint clamp (consisting of Rad17, Mec3, and Ddc1) onto partial duplex DNA in an ATP-dependent manner.The DNA damage checkpoint response arrests cells at appropriate points in the cell cycle to allow recovery of the integrity of the DNA before re-entering the cell cycle.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human RFC3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD11460
(40 western blots)
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