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Anti-Human SRC3 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human SRC3 Antibody  ABD11461
    Detection of human SRC3 in nuclear extracts of HeLa cells by Western blotting with Rabbit anti Human SRC3 . Immunoprecipitation of the nuclear extracts was done using AHP883 followed by resolution by SDS-PAGE , staining with Coomassie and the SRC3 band confirmed by mass spectroscopy
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6Q9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 155293 Da
Additional Information
Purification Antisera to human SRC3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to a region within human SRC3 encoded by exon 16.
Shelf Life 12 months from date of reconstitution.
Gene ID 8202
Other Names Nuclear receptor coactivator 3, NCoA-3,, ACTR, Amplified in breast cancer 1 protein, AIB-1, CBP-interacting protein, pCIP, Class E basic helix-loop-helix protein 42, bHLHe42, Receptor-associated coactivator 3, RAC-3, Steroid receptor coactivator protein 3, SRC-3, Thyroid hormone receptor activator molecule 1, TRAM-1, NCOA3, AIB1, BHLHE42, RAC3, TRAM1
Target/Specificity Rabbit anti-Human SRC3 antibody recognizes human nuclear receptor coactivator 3, also known as SRC3, NCoA3, Amplified in breast cancer 1 protein, AIB1, CBP-interacting protein, Class E basic helix-loop-helix protein 42, Receptor-associated coactivator 3. Steroid receptor coactivator protein 3 or Thyroid hormone receptor activator molecule 1. SRC3 is a 1423 amino acid ~160 kDa member of the steroid receptor coactivator family members which interact with nuclear receptors and enhance the transcription of target genes in a ligand-dependent manner. SRC3 has been shown to interact with several steroid receptors, such as oestrogen receptor alpha and progesterone receptor. Altered expression of SRC3 has been reported in a number of cancers, including breast cancer (Osborneet al.2003). In addition, SRC3 interacts with IKK, suggesting that SRC3 may be involved in inflammatory and immune responses mediated by NF-kappaB (Wuet al.2002).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃. DO NOT FREEZE.
PrecautionsAnti-Human SRC3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11461
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