|Application ||WB, IHC-P|
|Calculated MW||92463 Da|
|Purification||Antisera to human ACE2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a sequence within the amino terminus of human ACE2.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Angiotensin-converting enzyme 2, 184.108.40.206, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2, ACE2|
|Target/Specificity||Rabbit anti-Human ACE2 antibody recognizes human Angiotensin-converting enzyme 2, also known as ACE2, ACE-related carboxypeptidase or Metalloprotease MPROT15. ACE2 is a 788 amino acid ~100 kDa carboxypeptidase expressed in a range of tissues including heart, kidney, testis and the gastrointestinal system. ACE2 is a homologue of ACE (Angiotensin-converting enzyme 1), although it has a distinct catalytic activity. ACE2 catalyzes the cleavage of active angiotensin II into angiotensin 1-7, which may counteract the effects of ACE by increasing vasodilatation.ACE2 serves as the cellular entry point for the severe acute respiratory syndrome (SARS) virus, functioning as a receptor for the SARS Spike protein (Turneret al.2004).|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human ACE2 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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