|Calculated MW||34095 Da|
|Purification||Antisera to phosphorylated CDC2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic phosphopeptide corresponding to an amino acid sequence within CDC2 which includes phosphorylated Tyr15.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Cyclin-dependent kinase 1, CDK1, 18.104.22.168, 22.214.171.124, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDK1, CDC2, CDC28A, CDKN1, P34CDC2|
|Target/Specificity||Rabbit anti-phosphorylated CDC2 antibody recognizes Cyclin-dependent kinase 1, also known as Cell division control protein 2 homolog, CDC2, CDK1 or p34 protein kinase. Rabbit anti-phosphorylated CDC2 antibody recognizes CDC2 only when phosphorylated at Tyr15.CDC2 is a serine kinase which plays an important role in the regulation of the cell cycle, mediating progression from G2 to M phase. Phosphorylation of tyrosine 15 results in inactivation of CDC2.|
|Preservative & Stabilisers||0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-CDC2 (pTyr15) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Fletcher, L. et al. (2002) Abolishment of the Tyr-15 inhibitory phosphorylation site on cdc2 reduces the radiation-induced G2 delay, revealing a potential checkpoint in early mitosis.Cancer Res. 62: 241-250.
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