|Calculated MW||44888 Da|
|Purification||Antisera to phosphorylated ELK-1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic phosphopeptide corresponding to an amino acid sequence within ELK-1 which includes phosphorylated Ser383.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||ETS domain-containing protein Elk-1, ELK1|
|Target/Specificity||Rabbit anti-phosphorylated ELK-1 antibody recognizes rat ETS domain-containing protein Elk-1 (ELK-1) when phosphorylated at serine 383.ELK-1 is a member of the ternary complex factor (TCF) family of transcription factors, which is thought to play a role in mediating gene expression in response to growth factors. ELK-1 can be phosphorylated at serine 383 and 389 in its C-terminal region in response to the activation of extracellular signal-regulated kinase (ERK) proteins. Phosphorylation of ELK-1 results in an increase in its transcriptional activity, leading to the transcription of growth-related proteins, such as c-Fos.|
|Preservative & Stabilisers||0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-ELK-1 (pSer383) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Yang, S. et al. (1998) The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.Mol. Cell. Biol. 18: 710 - 720.
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