|Calculated MW||43653 Da|
|Purification||Antisera to human phosphorylated p53 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic phosphopeptide corresponding to an amino acid sequence within p53 which includes the phosphorylated residue Ser392.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, TP53, P53|
|Target/Specificity||Rabbit anti-phosphorylated p53 antibody recognizes p53, when phosphorylated at serine 392.The tumour suppressor protein p53, is expressed ubiquitously and plays an important role in blocking proliferation of damaged cells. Phosphorylation of p53 at serine 392 is reported in response to diverse stresses, for example UV irradiation.|
|Preservative & Stabilisers||0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-p53 (pSer392) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Jaiswal, J. et al. (2001) p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents.J. Biol. Chem. 276: 18193-18199.
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