|Calculated MW||97295 Da|
|Purification||Antisera to phosphorylated rat dynamin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic phosphopeptide corresponding to an amino acid sequence within dynamin which includes phosphorylated Ser778.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Dynamin-1, 18.104.22.168, B-dynamin, D100, Dynamin, brain, Dnm1, Dnm|
|Target/Specificity||Sheep anti-phosphorylated dynamin antibody recognizes rat dynamin when phosphorylated at serine 778.Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.|
|Preservative & Stabilisers||0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Dynamin (pSer778) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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1. Marland, J.R. et al. (2016) Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome.PLoS One. 11 (1): e0147974.
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