Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.Anti-Synapsin I (pSer9) Antibody
Rabbit Anti-Rat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P09951 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Polyclonal IgG |
| Calculated MW | 73988 Da |
| Purification | Antisera to phosphorylated synapsin I were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. |
|---|---|
| Immunogen | Synthetic phosphopeptide corresponding to an amino acid sequence within Synapsin I which includes the phosphorylated residue Ser9. |
| Shelf Life | 12 months from date of reconstitution. |
| Gene ID | 24949 |
| Other Names | Synapsin-1, Synapsin I, Syn1 |
| Target/Specificity | Rabbit anti-phosphorylated Synapsin I antibody recognizes rat Synapsin I, when phosphorylated at serine 9.Synapsin I is a neuron-specific phosphoprotein which is associated with synaptic vesicles in the central and peripheral nervous system and is involved in the regulation of synaptic vesicle availability, and thought to play a key role in brain plasticity.Synapsin I is phosphorylated at serine 9 by cAMP-dependent protein kinase and calcium calmodulin kinase I. |
| Preservative & Stabilisers | 0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol |
| Storage | Store at +4℃ or at -20 ℃. |
| Precautions | Anti-Synapsin I (pSer9) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abgent.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1. Jovanovic, J.N. et al. (2001) Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+ -dependent glutamate release in isolated nerve terminals.J. Neurosci. 21: 7944 - 7953. 2. Kao, H.T. et al. (2002) A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth.Nature Neurosci. 5: 431 - 437. 3. Menegon, A. et al. (2000) Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals.J. Cell Sci. 113: 3573 - 3582.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Request Quote Here
Ordering Information
Other Products
Shipping Information
