|Calculated MW||101579 Da|
|Purification||Antisera to phosphorylated GluR1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by sequential affinity chromatography on phospho- and dephosphopeptide affinity columns.|
|Immunogen||Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes the phosphorylated residue Ser831.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1, Gria1, Glur1|
|Target/Specificity||Rabbit anti-phosphorylated GluR1 antibody recognizes rat glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.GluR1, widely expressed throughout the nervous system is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses.Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.|
|Preservative & Stabilisers||0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-GluR1 (pSer831) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Castellani, G.C. et al. (2001) A biophysical model of bidirectional synaptic plasticity: Dependence on AMPA and NMDA receptors.Proc. Natl. Acad. Sci. USA. 98: 12772 - 12777.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.
Request Quote Here