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>   home   >   Products   >   Primary Antibodies   >   Anti-Tryptophan Hydroxylase (pSer58) Antibody    

Anti-Tryptophan Hydroxylase (pSer58) Antibody

Rabbit Anti-Rabbit Polyclonal Antibody

  • WB - Anti-Tryptophan Hydroxylase (pSer58) Antibody  ABD11488
    Western blot of recombinant tryptophan hydroxylase in bacterial lysate incubated in the absence and presence of PKA showing phosphospecific immunolabeling of the ~55 kDa protein phosphorylated at Ser58
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17290
Reactivity Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 51118 Da
Additional Information
Purification Antisera to phosphorylated tryptophan hydroxylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Synthetic phosphopeptide corresponding to an amino acid sequence within Tryptophan Hydroxylase which includes the phosphorylated residue Ser58.
Shelf Life 12 months from date of reconstitution.
Gene ID 100009100;100101558
Other Names Tryptophan 5-hydroxylase 1,, Tryptophan 5-monooxygenase 1, TPH1, TPH
Target/Specificity Rabbit anti-phosphorylated tryptophan hydroxylase antibody recognizes tryptophan hydroxylase (TPH), when phosphorylated at serine 58.TPH catalyses the 5-hydroxylation of tryptophan, in the first stage in indolamine biosynthesis (e.g. serotonin and melatonin). The activity of TPH is enhanced by phosphorylation of Ser58, by cAMP dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CAMKII).
Preservative & Stabilisers 0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Tryptophan Hydroxylase (pSer58) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Banik, U. et al. (1997) Interaction of phosphorylated tryptophan hydroxylase with 14-3-3 proteins.
J. Biol. Chem. 272: 26219 - 26225.

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Cat# ABD11488
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