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>   home   >   Products   >   Primary Antibodies   >   Anti-Rat GABA A Receptor beta 2 (C-Terminal) Antibody    

Anti-Rat GABA A Receptor beta 2 (C-Terminal) Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Rat GABA A Receptor beta 2 (C-Terminal) Antibody  ABD11493
    Western blot of 5μg of rat cerebellum showing specific immunolabelling of the ~55 kDa beta 2 subunit of the GABA-R
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P63138
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 54633 Da
Additional Information
Purification Antisera to GABAA receptor were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Fusion protein within the cytosolic loop of rat GABAA receptor beta 2 subunit.
Shelf Life 12 months from date of reconstitution.
Gene ID 25451
Other Names Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2, Gabrb2, Gabrb-2
Target/Specificity ABD11493 is specific for the beta 2 subunit of rat gamma-aminobutyric acid A (GABAA) receptor. GABAA receptors are GABA gated chloride channels, which are important mediators of neuronal inhibition in the mammalian central nervous system. Activation of the GABAA site results in increased intracellular chloride concentration and hyperpolarization of the cell. GABAA receptors are pentameric structures assembled from a family of distinct subunits. At least fourteen distinct subunits have been identified, which show distinct patterns of temporal and spatial expression.GABAA receptors may be modulated by several drug types including benzodiazepines and barbiturates, and by phosphorylation by protein kinase C (PKC) and protein kinase A (PKA).
Preservative & Stabilisers 0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat GABA A Receptor beta 2 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Burt, D.R. et al. (1991) GABAA receptor subtypes: from pharmacology to molecular biology.
FASEB. J. 5: 2916-2923.

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Cat# ABD11493
(40 western blots)
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