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>   home   >   Products   >   Primary Antibodies   >   Anti-Glycine Receptor alpha 1/2 (N-Terminal) Antibody    

Anti-Glycine Receptor alpha 1/2 (N-Terminal) Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Glycine Receptor alpha 1/2 (N-Terminal) Antibody  ABD11495
    Western blot of rat spinal cord snd hippocamapl lysates showing specific immunolabeling of the ~48 kDa glycine receptor in spinal cord.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07727
Other Accession P22771
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 52617 Da
Additional Information
Other Species M,H
Purification Antisera to rat glycine receptor (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to the N-terminal region of rat glycine receptor alpha 1 subunit.
Shelf Life 12 months from date of reconstitution.
Gene ID 25674
Other Names Glycine receptor subunit alpha-1, Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit, Glra1, Glyr
Target/Specificity Rabbit anti-glycine receptor recognises an epitope within the N-terminal region (NT) of glycine receptor alpha 1 and alpha 2 subunits.Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation.Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Glycine Receptor alpha 1/2 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Chen, Z. et al. (2004) Molecular determinants of proton modulation of glycine receptors.
J. Biol. Chem. 279: 876 - 883.

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Cat# ABD11495
(40 western blots)
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