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Anti-Tyrosine Hydroxylase Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Tyrosine Hydroxylase Antibody  ABD11497
    Western blot of rat caudate lysate showing specific immunolabeling of the ~60 kDa tyrosine hydroxylase protein
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04177
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 55966 Da
Additional Information
Other Species Mammalian
Purification Antisera to tyrosine hydroxylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Tyrosine hydroxylase purified from pheochromocytoma.
Shelf Life 12 months from date of reconstitution.
Gene ID 25085
Other Names Tyrosine 3-monooxygenase,, Tyrosine 3-hydroxylase, TH, Th
Target/Specificity ABD11497 is specific for Tyrosine hydroxylase (TH).Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain.Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson’s disease.
Preservative & Stabilisers 0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Tyrosine Hydroxylase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Xu, Z.Q. et al. (1998) Immunohistochemical studies on phosphorylation of tyrosine hydroxylase in central catecholamine neurons using site- and phosphorylation state- specific antibodies.
Neurosci. 82: 727-738. 2. Fan, W. et al. (2010) Structural and cellular features in metaphyseal and diaphyseal periosteum of osteoporotic rats.
J Mol Histol. 41: 51-60. 3. Kim, S.M. et al. (2009) Dense-core vesicle proteins IA-2 and IA-2{beta} affect renin synthesis and secretion through the {beta}-adrenergic pathway.
Am J Physiol Renal Physiol. 296: F382-9.

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Cat# ABD11497
(40 western blots)
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