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Anti-Human Dopamine Transporter (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human Dopamine Transporter (C-Terminal) Antibody  ABD11498
    Western blot of 6μg of human caudate lysate showing specific immunolabeling of the ~88 kDa DAT protein
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q01959
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 68495 Da
Additional Information
Other Species Pr,M
Purification Antisera to human dopamine transporter (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Keyhole limpet haemocyanin conjugated synthetic peptide corresponding to the C-terminus region (CT) of human dopamine transporter.
Shelf Life 12 months from date of reconstitution.
Gene ID 6531
Other Names Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3, SLC6A3, DAT1
Target/Specificity ABD11498 recognises an epitope within the C-terminal region (CT) of dopamine transporter (DAT), also known as solute carrier family 6.DAT is principally expressed in the presynaptic membrane of dopaminergic nerve terminals, where it mediates the rapid removal of dopamine from the synaptic cleft after neuronal stimulation. As such, DAT plays an important role in regulating the availability of dopamine in the synaptic cleft and thus in modulating the physiological functions of dopamine.The reuptake of dopamine by DAT is inhibited by psychostimulants such as cocaine and amphetamine.
Preservative & Stabilisers 0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Dopamine Transporter (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Mozley, L. H. et al. (2001) Striatal dopamine transporters and cognitive functioning in healthy men and women.
Am. J. Psychiatry 158: 1492 - 1499.

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Cat# ABD11498
(40 western blots)
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