|Application ||WB, IHC-P|
|Calculated MW||56685 Da|
|Purification||Antisera to human XIAP were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a thirteen amino acid sequence with the C-terminal region of human XIAP.|
|Shelf Life||18 months from date of despatch.|
|Other Names||E3 ubiquitin-protein ligase XIAP, 6.3.2.-, Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP, XIAP, API3, BIRC4, IAP3|
|Target/Specificity||ABD11500 is specific for human X-chromosome linked inhibitor of apoptosis (XIAP). XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs). Regulators of XIAP activity include XAF-1 and Smac. ABD11500 detects a band of approximately 57KDa in human kidney lysates.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-XIAP (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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