|Application ||WB, IHC-P|
|Calculated MW||21995 Da|
|Purification||Antisera to human BID were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to fourteen amino acid residues within the C-Terminal region of human Bid.|
|Shelf Life||18 months from date of despatch.|
|Other Names||BH3-interacting domain death agonist, p22 BID, BID, BH3-interacting domain death agonist p15, p15 BID, BH3-interacting domain death agonist p13, p13 BID, BH3-interacting domain death agonist p11, p11 BID, BID|
|Target/Specificity||ABD11501 is specific for human BH3 interacting domain death agonist (Bid). Bid is a pro-apoptotic protein within the Bcl-2 family, which plays an important role in bridging the extrinsic and intrinsic apoptosis pathways. Death receptors, such as Fas and tumor necrosis factor receptor-1, can activate Bid through proteolytic cleavage by caspase-8. Truncated Bid is translocated to the mitochondria, resulting in the induction of cytochrome c release.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-BID (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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