|Application ||FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Con A stimulated canine T cells.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Rat anti-Dog CD90, clone YKIX337.217 recognizes the canine Thy-1 cell surface antigen, also known as CD90. CD90 is a 20-30 kDa glycoprotein expressed by peripheral T lymphocytes, monocytes, thymocytes and vascular endothelium in dogs.Rat anti-Dog CD90, clone YKIX337.217 has been demonstrated to deplete T cells when administered in vivo(Watsonet al.1993), and to block Con A driven T cell proliferation in vitro.Rat anti-Dog CD90, clone YKIX337.217 is a useful clone for the immunophenotyping of cells and discrimination between a wide variety of lymphoploriferative disorders in dogs (Villiers 2006).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Dog CD90 Antibody, clone YKIX337.217 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Cobbold, S. and Metcalfe, S. (1994) Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW).Tissue Antigens 43: 137-154. 2. Carneiro, C.M. et al. (2007) Differential impact of metacyclic and blood trypomastigotes on parasitological, serological and phenotypic features triggered during acute Trypanosoma cruzi infection in dogs.Acta Trop. 101: 120-9. 3. Kang, J.W. et al. (2008) Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells.Stem Cells Dev. 17: 681-93. 4. Sanchez, M.A. et al. (2004) Organ-specific immunity in canine visceral leishmaniasis: analysis of symptomatic and asymptomatic dogs naturally infected with Leishmania chagasi.Am J Trop Med Hyg. 70: 618-24. 5. Giunchetti, R.C. et al. (2008) Histopathology, parasite density and cell phenotypes of the popliteal lymph node in canine visceral leishmaniasis.Vet Immunol Immunopathol. 121: 23-33. 6. Reis, A.B.
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