|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Rat anti-Dog CD11/CD18 antibody, clone YKIX490.6.4 recognizes the canine leukocyte cell adhesion molecule (LeuCAM) composed of the ~180 kDa CD11a chain complexed with the ~95 kDa common beta chain CD18. The CD11a/CD18 complex is also known as LFA-1.Rat anti-Dog CD11/CD18 has been reported to block T cell proliferation, cytotoxic T lymphocyte (CTL) lysis, antibody dependent cell mediated cytotoxic (ADCC) lysis and homotypic cell adhesion (Cobboldet al.1994)|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Dog CD11/CD18 Antibody, clone YKIX490.6.4 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Cobbold, S. & Metcalfe, S. (1994) Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW).Tissue Antigens. 43 (3): 137-54. 2. Huang, Y.C. et al. (2008) CD5-low expression lymphocytes in canine peripheral blood show characteristics of natural killer cells.J Leukoc Biol. 84: 1501-10. 3. Modiano, J.F. (2005) Early detection of hemangiosarcoma and angiosarcomaPatent application 11/662529 4. Fiuza, J.A. et al. (2013) Induction of immunogenicity by live attenuated Leishmania donovani centrin deleted parasites in dogs.Vaccine. 31: 1785-92.
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