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Anti-Pig CD2a Antibody, clone MAC83 (Ascites)

Rat Anti-Pig Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, CHIP, Func
Reactivity Pig
Host Rat
Clonality Monoclonal
Isotype IgM
Clone Names MAC83
Additional Information
Immunogen Pig T lymphoblasts.
Shelf Life 18 months from date of despatch.
Target/Specificity Rat anti-Pig CD2a, clone MAC83 recognizes pig CD2a, a single pass type 1 transmembrane protein of ~50 kDa. Porcine CD2 is a lymphocyte expressed cellular adhesion receptor, originally identified as a lymphocyte restricted sheep red blood cell receptor (Binnset al.1982).Porcine CD2, also known as LFA-2 interacts with its ligand CD58 also known as LFA-3 in a manner analogous to that seen in mice (Senet al.1989).Rat anti-Pig CD2a, clone MAC83 was clustered to CD2a at the first International Swine CD Workshop based on its cell distribution, antigen immunoprecipitation and its ability to completely inhibit the biding of another anti-porcine CD2a clone, MSA4 (Pescowitzet al.1994).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Pig CD2a Antibody, clone MAC83 (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Lunney, J.K. et al. (1994) Overview of the First International Workshop to Define Swine Leukocyte Cluster of Differentiation (CD) Antigens
Vet. Immunol. Immunopathol. 43: 193 - 206 2. Pescovitz, M.D. et al. (1994) Analysis of monoclonal antibodies reactive with the porcine CD2 antigen.
Vet Immunol Immunopathol. 43: 229-32. 3. Saalmuller, A. (1996) Characterization of swine leukocyte differentiation antigens.
Immunology Today. 17: 352-354. 5. Li, B. et al. (2010) Immunological response of sheep to injections of plasmids encoding Toxoplasma gondii SAG1 and ROP1 genes.
Parasite Immunol. 32: 671-83. 6. Saalmüller, A. et al. (1998) Overview of the Second International Workshop to define swine cluster of differentiation (CD) antigens.
Vet Immunol Immunopathol. 60: 207-28. 7. Lunney, J.K. (1993) Characterization of swine leukocyte differentiation antigens.
Immunol Today. 14: 147-8.4. Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39: 54.

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Cat# ABD11547
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